By Guy F. Webster, Anthony V. Rawlings
Addressing the most ordinarily encountered stipulations noticeable through the dermatologist, this resource analyzes the pathophysiology, review, prognosis, scientific positive factors, and keep watch over of pimples. With full-color illustrations, this resource delves into the to be had remedies for tough circumstances of pimples and scarring and offers professional discussions of administration regimens together with topical and systemic cures, laser remedies, and new medicines.
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(BMJ Books) Royal Infirmary, united kingdom. bargains a concise assessment of the entire necessities of dermatology, written for non-dermatologists and first care physicians. Discusses a number of universal stipulations equivalent to psoriasis, eczema, pimples and rosacea, bacterial an infection, viral an infection, tropical dermatology, and extra.
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Extra resources for Acne and its therapy
J Clin Endocrinol Metab 1993; 76:524– 528. 94. Holland DB, Cunliffe WJ, Norris JFB. Differential response if sebaceous glands to exogenous testosterone. Br J Dermatol 1998; 139:102– 103. 95. Henderson CA, Knaggs H, Clark A, Highet AS, Cunliffe WJ. Apert’s syndrome and androgen receptor staining of the basal cells of sebaceous glands. Br J Dermatol 1995; 132(1):139– 143. 96. Whitaker SB, Vigneswaran N, Singh BB. Androgen receptor status of the oral sebaceous glands. Am J Dermatopathol 1997; 19(4):415– 418.
Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides. J Invest Dermatol 1986; 87:733 – 736. 85. Stewart ME, Greenwood R, Cunliffe WJ, Strauss JS, Downing DT. Effect of cyproterone acetate-ethinyl estradiol treatment on the proportions of linoleic and sebaleic acids in various skin surface lipid classes. Arch Dermatol Res 1986; 278:481– 485. 86. Kotani A, Kusu F. HPLC with electrochemical detection for determining the distribution of free fatty acids in skin surface lipids from the human face and scalp.
However, it has not been possible to demonstrate differences in receptor levels that explain androgen dependent dermatoses, such as acne or the different rates of sebum production in different individuals. There is a strong correlation between sebum excretion rate and acne grade (99,100), but it has not been possible FIGURE 3 A schematic representation of potential pathways in sebocytes that can regulate lipogenesis. Abbreviations: CAMP, cyclic adenosine monophosphate; CRH, corticotrophic releasing hormone; EGF, epidermal growth factor; FGF, fibroblast growth factor; GH, growth hormone; IGF, insulin-like growth factors; KGF, keratinocyte growth factor; MSH, melanocyte stimulating hormone; PPARs, peroxisome proliferator-activated receptors; TGF, transforming growth factor.
Acne and its therapy by Guy F. Webster, Anthony V. Rawlings