By George F. Vande Woude (ed.), George Klein (ed.)
Quantity sixty one of "Advances in melanoma study" comprises insurance of the subsequent: molecular ways to melanoma treatment, radiation resistance, melanoma prevention learn trials, mammalian gene amplification, retinoblastoma gene functionality, molecular genetic foundation of breast melanoma, and tumour merchandising by way of okadaic acid classification compounds.
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MOLECULAR GENETICS IN BREAST CANCER 39 B. POINTMUTATIONS T h e only point mutations thus far detected in human cancer are those in the rm family of genes, in the p53 gene and in the prohibitin gene (for the latter two, see Section 11,D). Mutations in the rm genes are rare in human breast cancer. , 1988). , 1984). Two more breast cancer cell lines have been shown to contain ras gene mutations, affecting the c-Ki-rm gene in both cases. , 1989). From this it appears that rm gene mutations affect only a minor proportion of all tumors.
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Advances in Cancer Research, Vol. 61 by George F. Vande Woude (ed.), George Klein (ed.)